Yongsheng Chen, PhD

Yongsheng Chen, PhD

ys.chen@wayne.edu

Phone: 313-577-2074

Fax: 313 745-4216 (fax)

Yongsheng Chen, PhD

Office Address

Department of Neurology

8C UHC
4201 St Antoine Blvd.
Detroit, Michigan 48201

Narrative Bio

Dr. Yongsheng Chen is an Assistant Professor (Research) in Neurology as of December 1, 2018. Dr. Chen received his PhD in Biomedical Engineering from Northeastern University, Shenyang of the Liaoning Province in China.

He was a Research Scientist at the MRI Institute for Biomedical Research from March 2017 until November 2018 where he established STAGE protocols for different vendors’ MRI scanners, distributed them to 21 sites all over the world, and worked closely with these sites to improve, verify and validate the protocols for different neuro-imaging situations.

Dr. Chen was a Research Assistant in the Department of Radiology at Wayne State University from April 2015 until November 2018 where he developed a new simultaneous Magnetic Resonance Angiography and Venography (MRAV) pulse sequence for cerebral and peripheral vessel imaging. He also developed a new quantitative imaging method referred to as “Strategically Acquired Gradient Echo (STAGE) imaging” as well as the post-processing software using MATLAB and Visual Studio C# including the processing of T1 mapping, RF variation mapping, multi-echo Quantitative Susceptibility Mapping (QSM), Susceptibility Weighted Imaging (SWI), and MRAV. Another key development that he contributed to was a new method to image the human retina in vivo at 3T with a spatial resolution less than 100 microns.

Before joining Wayne State University, he worked in the MRI industry for 13 years in software design, MR pulse sequence design, image reconstruction, software verification and validation, software quality control, and 510(k) premarket submissions.
 

Academic Rank

Assistant Professor, Department of Neurology

Other Information

Research Assistant — MR Research Facility, Wayne State University 2015 — 2018
Research Scientist — The MRI Institute for Biomedical Research 2017 — 2018
Software R&D Manager — Liaoning Kampo Medical System Co., Ltd. 2010 — 2015
Senior Software Engineer — Philips and Neusoft Medical Systems Co., Ltd. 2004 — 2010
Software Engineer — Neusoft Medical Systems Co., Ltd. 2001 — 2004

Undergraduate

Northeastern University, China — B.S, Computer Engineering 1998 — 2002

Graduate

Northeastern University, China — M.S., Computer Engineering 2006 — 2009

Northeastern University, China — Ph.D., Biomedical Engineering 2013 — 2018
 

Specialties

Magnetic Resonance Imaging

 

Publications

(SELECTED)

Peer-Reviewed Journal Articles:

[1] Y. Chen, S. Liu, Y. Wang, Y. Kang, and E. M. Haacke, "STrategically Acquired Gradient Echo (STAGE) imaging, part I: Creating enhanced T1 contrast and standardized susceptibility weighted imaging and quantitative susceptibility mapping," Magnetic Resonance Imaging, vol. 46, pp. 130-39, 2018.

[2] Y. Chen, S. Liu, S. Buch, J. Hu, Y. Kang, and E. M. Haacke, "An interleaved sequence for simultaneous Magnetic Resoannce Angiography (MRA), Susceptibility Weighted Imaging (SWI) and Quantitative Susceptibility Mapping (QSM)," Magnetic Resoannce Imaging, vol. 47, pp. 1-6, 2018.

[3] Y. Wang, Y. Chen, D. Wu, Y. Wang, S. K. Sethi, G. Yang, et al., "STrategically Acquired Gradient Echo (STAGE) imaging, part II: Correcting for RF inhomogeneities in estimating T1 and proton density," Magnetic Resonance Imaging, vol. 46, pp. 140-50, 2018.

[4] S. Liu, S. Buch, Y. Chen, H. S. Choi, Y. Dai, C. Habib, et al., "Susceptibility‐weighted imaging: current status and future directions," NMR in Biomedicine, vol. 30, 2017.

[5] Buch S, Chen Y, Mark Haacke E. Susceptibility mapping of the dural sinuses and other superficial veins in the brain. Magn Reson Imaging 2019;57:19–27.

Book Chapters:

[1] S. Buch, S. Liu, Y. Chen, K. Ghassaban, and E. M. Haacke, "T2*: Susceptibility Weighted Imaging and Quantitative Susceptibility Mapping," in Quantitative MRI of the brain: principles of physical measurement, M. Cercignai, N. G. Dowell, and P. S. Tofts, Eds., 2 ed: CRC Press, 2018.

[2] E. M. Haacke, D. Utriainen, S. Buch, and Y. Chen, "MR imaging of intracranial and extracranial veins," in Latest Frontiers of Hemodynamics, Imaging and Treatment of Obstructive Venous Disease, A. Giaquinta, B.-B. Lee, C. Setacci, P. Veroux, and P. Zamboni, Eds., 1st ed: Edizioni Minerva Medica, 2018.

Peer-Reviewed Conference Proceedings:

[1] Y. Chen, S. Liu, Y. Kang, and E. M. Haacke, "A rapid, robust multi-echo phase unwrapping method for quantittive susceptibility mapping (QSM) using strategically acquired gradient echo (STAGE) data acquisition," SPIE Medical Imaging, 2018, p. 105732U, doi:10.1117/12.2292951.

[2] Y. Chen, S. Liu, Y. Kang, and E. M. Haacke, "An Interleaved Sequence for Simultaneous MRA, SWI and QSM," in Int. Soc. Magn. Res. Med. Scientific Meeting, Hawaii, USA, 2017, p1215.

[3] Y. Chen, Y. Song, J. Hu, Y. Ye, Y. Wang, B. A. Berkowitz, et al., "Ultra-High Spatial Resolution Imaging in Vivo of Human Retina at 3T," in Int. Soc. Magn. Res. Med. Scientific Meeting, Hawaii, USA, 2017, p2268.

[4] S. Buch, Y. Chen, and E. M. Haacke, "Susceptibility Mapping of the Dural Sinuses and Other Major Veins in the Brain," in Int. Soc. Magn. Res. Med. Scientific Meeting, Hawaii, USA, 2017

[5] Y. Chen, S. Xia, L. Wang, S. K. Sethi, M. Fawaz, S. Liu, et al., "Automatic Detection of Cerebral
Microbleeds (CMBs) using STrategically Acquired Gradient Echo (STAGE) imaging," in American Society of Neuroradiology (ASNR), Vancouver, BC, Canada, 2018, pp. 211.

[6] P. Huang, J. Lyu, H. Li, Y. Chen, S. Liu, C. Zhang, et al., "Highly Accelerated 3D MR Angiography Using Multi-Channel Blind Deconvolution," in Int. Soc. Magn. Res. Med. Scientific Meeting, Paris, France, 2018, p. p3356.

[7] A. Sun, F. Huang, Y. Wang, W. Xu, Y. Wang, Y. Chen, et al., "Methods to accelerate STAGE: Toward 8 min for Twelve 3D images on 1.5T," in Int. Soc. Magn. Res. Med. Scientific Meeting, Paris, France, 2018, p. p0319.

[8] Y. Wang, F. Huang, W. Xu, T. Li, H. Guo, Y. Chen, et al., "STAGE Imaging at 1.5T: A Rapid Brain Protocol Providing More Images As Well As Quantitative Data," in Int. Soc. Magn. Res. Med. Scientific Meeting, Paris, France, 2018, p. p2750.

[9] N. M. Wiseman, S. Buch, Y. Chen, E. M. Haacke, and Z. Kou, "Magnetic resonance angiography and venography was not useful for correcting underestimated susceptibility measurements of sub-voxel objects on quantitative susceptibility maps," in Int. Soc. Magn. Res. Med. Scientific Meeting, Paris, France, 2018, p1868.

[10] W. Xu, Y. Wang, F. Huang, T. Li, H. Guo, Y. Chen, et al., "A rapid scan for simultaneous MRAV, MRA, tSWI, and QSM on 1.5T," in Int. Soc. Magn. Res. Med. Scientific Meeting, Paris, France, 2018, p1871.

[11] C. Wang, S. Liu, Y. Chen, S. Buch, E. M. Haacke, and Q. Yang, "Intraplaque Hemorrhage and Calcification Detection with Quantitative Susceptibility Mapping," in Int. Soc. Magn. Res. Med. Scientific Meeting, Paris, France, 2018, p0491.

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